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INNO-220

CAS:

Ref. TM-T211026

INNO-220
Targetmol

Product Information

Name:INNO-220
Brand:Targetmol
Description:INNO-220 is an orally active, CRBN-dependent molecular glue degrader that targets CK1α. By degrading CK1α, INNO-220 induces cell cycle arrest at the G0/G1 phase and triggers apoptosis (Apoptosis). It disrupts the assembly and function of the CARD11/BCL10/MALT1 complex, inhibiting the NF-κB signaling pathway in T cells and lymphoma cells with activating mutations in CARD11. INNO-220 offers a novel direction for lymphoma research.
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Chemical properties

Molecular weight:400.43
Formula:C23H20N4O3
Color/Form:Solid

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