RN341
Ref. TM-T211251
Product Information
Name:RN341
Brand:Targetmol
Description:RN341 is a LRRK2-specific type II kinase inhibitor (IC50 of 296 nM). It prevents the phosphorylation of LRRK2 by stabilizing an open conformation, thereby avoiding S935 dephosphorylation. Additionally, RN341 rescues LRRK2-mediated kinesin motility blockage by preventing microtubule binding. This compound effectively inhibits both wild-type and G2019S LRRK2 at the cellular level, offering a novel avenue for Parkinson's disease research.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Color/Form:Odour Solid
Technical inquiry about: RN341
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