MI1013
Ref. TM-T211438
Product Information
Name:MI1013
Brand:Targetmol
Description:MI1013 is a PROTAC PXR degrader with a DC50 of 89 nM and a Dmax of 82%. It degrades PXR in human liver cancer RG cells (HepaRG) and modulates CYP3A4 promoter activity with specificity and safety through PXR degradation. MI1013 influences key genes involved in sulfate conjugation (e.g., SULT1E1), bile acid synthesis (CYP7A1), gluconeogenesis (PCK1), ketogenesis (HMGCS20), and hepatocyte proliferation (MKI67).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Color/Form:Odour Solid
Technical inquiry about: MI1013
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