Product Information
Name:ASIC1a antagonist-1
Brand:Targetmol
Description:ASIC1a antagonist-1 (Compound 5b) is an orthosteric non-competitive antagonist of the acid-sensing ion channel 1a (ASIC1a) with an IC50 of 27 nM at pH 6.7. It alters the pH dependency of ASIC1a activation and suppresses its maximum response. Additionally, ASIC1a antagonist-1 completely inhibits the induction of long-term potentiation (LTP) in the CA3-CA1 pathway. This compound is useful for research into brain diseases and pathologies.
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Chemical properties
Molecular weight:499.86
Formula:C23H29Cl3N4O2
Technical inquiry about: ASIC1a antagonist-1
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