Product Information
Name:PNR-3-80
Brand:Targetmol
Description:PNR-3-80 is a selective inhibitor of apoptotic endonuclease G (EndoG), with an IC50 of 0.67 μM, showing greater inhibition than against DNase I. It exhibits no inhibitory activity against DNase II, RNase A, proteases, lactate dehydrogenase, and superoxide dismutase 1. PNR-3-80 effectively protects human prostate cancer cells from cell death induced by Cisplatin and Docetaxel and inhibits DNA damage and autophagy (autophagy) prompted by Etoposide. This compound is applicable in studies of cellular damage.
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Chemical properties
Molecular weight:459.90
Formula:C24H14ClN3O3S
Color/Form:Solid
Technical inquiry about: PNR-3-80
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