Loxapine

CAS: 1977-10-2

Ref. TM-T21629

Product Information

• Name: Loxapine
• Synonyms: 2-Chloro-11-(4-Methylpiperazin-1-Yl)Dibenzo[B,F][1,4]Oxazepine, 2-Chloro-11-(4-Methylpiperazin-1-Yl)Dibenzo[B,F][1,4]Oxazepine Butanedioate (1:1), 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine, 2-Chloro-11-(4-methylpiperazino)dibenz[b,f][1,4]oxazepine, 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine, Adasuve, Brn 0626753, Cl 62362, Cloxazepine, Dibenz(b,f)(1,4)oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-, Dibenzacepin, Dibenzoazepine, Hf 3170, Hf3170, Hsdb 3111, Hydrofluoride 3170, Lossapina, Lossapina [DCIT], Loxapin, Loxapina, Loxapina [INN-Spanish], Loxapine [USAN:INN:BAN], Loxapinum, Loxapinum [INN-Latin], Loxitane, Loxitane IM, Lw 3170, Oxilapine, Rosup, S 805, Sum 3170, Unii-Ler583670J
• CAS: 1977-10-2

Description

Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class and structurally related to clozapine (which belongs to the chemically akin class of dibenzodiazepines).

• Brand: Targetmol

Chemical properties

• Molecular weight: 327.81
• Formula: C₁₈H₁₈ClN₃O
• Purity: 99.98%
• Color/Form: Pale Yellowish Crystals From Petroleum Ether Solid
• InChI: InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3
• InChI key: InChIKey=XJGVXQDUIWGIRW-UHFFFAOYSA-N
• SMILES: CN1CCN(C2=Nc3ccccc3Oc3ccc(Cl)cc32)CC1