ZW-18-116
Ref. TM-T217068
10mg
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50mg
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Product Information
Name:ZW-18-116
Brand:Targetmol
Description:ZW-18-116 (compound 9) is a dual-target PROTAC degrader focusing on the oncogenic proteins TRKA and RET. It induces the degradation of TRKA and RET by recruiting the CRBN E3 ligase. ZW-18-116 shows potent antiproliferative activity in various cancer cell lines harboring RET or TRKA fusion genes. This compound is applicable to research on RET or TRKA-related cancers such as thyroid, lung, and colon cancers.
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Chemical properties
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