FzM1
CAS: 1680196-54-6
Ref. TM-T24076
1mg | 41.00 € | ||
5mg | 78.00 € | ||
10mg | 106.00 € | ||
25mg | 185.00 € | ||
50mg | 346.00 € | ||
100mg | 516.00 € | ||
500mg | 1,133.00 € | ||
1ml*10 (DMSO) | 60.00 € |
Product Information
- FzM 1, FzM-1
FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2) by binding to an allosteric site on intracellular loop 3 (ICL3) of FZD4. This interaction changes the receptor's conformation and inhibits the WNT/β-catenin signaling pathway.
Chemical properties
Technical inquiry about: TM-T24076 FzM1
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