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Stem Cells
IHR-1
CAS: 548779-60-8
IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over …
Formula:
C20H12Cl4N2O2
Purity:
98.60%
Molecular weight:
454.12
Estimated delivery in United States, on Monday 28 Jun 2021
LY2109761
CAS: 700874-71-1
LY2109761 is a novel selective TGF- receptor type I/II (TRI/II) dual inhibitor with Ki of …
Formula:
C26H27N5O2
Purity:
99.83%
Color and Shape:
solid
Molecular weight:
441.52
Estimated delivery in United States, on Monday 28 Jun 2021
Astragaloside II
CAS: 84676-89-1
Astragaloside II is an effective MDR reversal agent and may be a potential adjunctive agent …
Formula:
C41H66O15
Purity:
99.70%
Color and Shape:
solid
Molecular weight:
798.95
Estimated delivery in United States, on Monday 28 Jun 2021
Monocrotaline
CAS: 315-22-0
Monocrotaline is a pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans …
Formula:
C16H23NO6
Purity:
99.59%
Color and Shape:
solid
Molecular weight:
325.36
Estimated delivery in United States, on Monday 28 Jun 2021
Kartogenin
CAS: 4727-31-5
Kartogenin is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent …
Formula:
C20H15NO3
Purity:
96.25%
Color and Shape:
solid
Molecular weight:
317.34
Estimated delivery in United States, on Monday 28 Jun 2021
Galunisertib
CAS: 700874-72-2
Galunisertib is an orally available inhibitor of TGFRI kinase (IC50: 56 nM) with potential antineoplastic …
Formula:
C22H19N5O
Purity:
99.85%
Color and Shape:
solid
Molecular weight:
369.42
Estimated delivery in United States, on Monday 28 Jun 2021
XMU-MP-1
CAS: 2061980-01-4
XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2.
Formula:
C17H16N6O3S2
Purity:
99.68%
Color and Shape:
solid
Molecular weight:
416.47
Estimated delivery in United States, on Monday 28 Jun 2021
SB 4
CAS: 100874-08-6
SB 4 is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)
Formula:
C14H10BrNOS
Purity:
99.24%
Color and Shape:
solid
Molecular weight:
320.2
Estimated delivery in United States, on Monday 28 Jun 2021
LY3200882
CAS: 1898283-02-7
LY3200882 is a highly selective inhibitor of TGF- receptor type 1 (TGFRI).
Formula:
C24H29N5O3
Purity:
99.46%
Color and Shape:
solid
Molecular weight:
435.52
Estimated delivery in United States, on Monday 28 Jun 2021
I3MT-3
CAS: 459420-09-8
I3MT-3 (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase …
Formula:
C17H14N2O2S
Purity:
99.86%
Molecular weight:
310.4
Estimated delivery in United States, on Monday 28 Jun 2021
Porcupine-IN-1
CAS: 2036044-77-4
Porcupine-IN-1 is an effective porcupine inhibitor (IC50: 0.50.2 nM).
Formula:
C25H19FN4O
Purity:
99.61%
Color and Shape:
solid
Molecular weight:
410.44
Estimated delivery in United States, on Monday 28 Jun 2021
SRI-011381 hydrochloride
CAS: 2070014-88-7
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of …
Formula:
C20H32ClN3O
Purity:
99.59%
Color and Shape:
solid
Molecular weight:
365.94
Estimated delivery in United States, on Monday 28 Jun 2021
IWP-L6
CAS: 1427782-89-5
IWP-L6 is an extremely effective Porcn inhibitor (EC50: 0.5 nM).
Formula:
C25H20N4O2S2
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
472.58
Estimated delivery in United States, on Monday 28 Jun 2021
IWP-O1
CAS: 2074607-48-8
IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation …
Formula:
C26H20N6O
Purity:
99.98%
Color and Shape:
solid
Molecular weight:
432.48
Estimated delivery in United States, on Monday 28 Jun 2021
BIO-013077-01
CAS: 746667-48-1
BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.
Formula:
C17H13N5
Purity:
99.87%
Color and Shape:
solid
Molecular weight:
287.32
Estimated delivery in United States, on Monday 28 Jun 2021
SIS3
CAS: 521984-48-5
SIS3, a selective Smad3 inhibitor, can attenuate TGF-1-dependent Smad3 phosphorylation and DNA binding. It has …
Formula:
C28H27N3O3·HCl
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
489.99
Estimated delivery in United States, on Monday 28 Jun 2021
BIBF0775
CAS: 334951-90-5
BIBF0775 is a selective TGF type I receptor (Alk5) inhibitor (IC50: 34 nM).
Formula:
C31H34N4O2
Purity:
99.45%
Color and Shape:
solid
Molecular weight:
494.64
Estimated delivery in United States, on Monday 28 Jun 2021
SIS3 free base
CAS: 1009104-85-1
SIS3 free base is a potent and selective Smad3 phosphorylation inhibitor. SIS3 free base inhibits …
Formula:
C28H27N3O3
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
453.53
Estimated delivery in United States, on Monday 28 Jun 2021
Pirfenidone
CAS: 53179-13-8
Pirfenidone is an inhibitor for TGF- production and TGF- stimulated collagen production. Pirfenidone inhibits fibroblast, …
Formula:
C12H11NO
Purity:
99.75%
Color and Shape:
solid
Molecular weight:
185.22
Estimated delivery in United States, on Monday 28 Jun 2021
SJ000291942
CAS: 425613-09-8
SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway. BMPs are …
Formula:
C16H15FN2O4
Purity:
99.25%
Color and Shape:
solid
Molecular weight:
318.3
Estimated delivery in United States, on Monday 28 Jun 2021
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