PF-04418948
CAS: 1078166-57-0
Ref. TM-T3306
| 2mg | 47.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 315.00 € | ||
| 100mg | 348.00 € | ||
| 1ml*10 (DMSO) | 73.00 € |
Estimated delivery in United States, on Thursday 16 May 2024
Product Information
Name:
PF-04418948
Synonyms:
- PF 04418948, PF04418948
- Pf 04418948
- 1-(4-Fluorobenzoyl)-3-[(6-Methoxynaphthalen-2-Yl)Oxymethyl]Azetidine-3-Carboxylic Acid
CAS:
Description:
PF-04418948 is a potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors; exhibits <30% binding at a diverse panel of GPCRs and ion channels at a concentration of 10 μM. Inhibits PGE2-induced increases in intracellular cAMP; reverses PGE2-invoked relaxation of mouse trachea (IC50 = 2.7 nM).
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
409.41
Formula:
C23H20FNO5
Purity:
99.45%
Color/Form:
Solid
InChI:
InChI=1S/C23H20FNO5/c1-29-19-8-4-17-11-20(9-5-16(17)10-19)30-14-23(22(27)28)12-25(13-23)21(26)15-2-6-18(24)7-3-15/h2-11H,12-14H2,1H3,(H,27,28)
InChI key:
InChIKey=LWJGMYMNSNVCEM-UHFFFAOYSA-N
SMILES:
COc1ccc2cc(OCC3(C(=O)O)CN(C(=O)c4ccc(F)cc4)C3)ccc2c1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
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