Vesnarinone

CAS: 81840-15-5

Ref. TM-T3465

Product Information

• Name: Vesnarinone
• Synonyms: OPC-8212, Arkin, Piteranometozine, 1-(1,2,3,4-Tetrahydro-2-oxo-6-quinolyl)-4-veratroylpiperazine, 1-(3,4-Dimethoxybenzoyl)-4-(1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)piperazine, 2(1H)-Quinolinone, 6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-3,4-dihydro-, 3,4-Dihydro-6-(4-(3,4-dimethoxybenzoyl)-1-piperazinyl)-2(1H)-quinolinone, 6-(4-(3,4-Dimethoxybenzoyl)-1-piperazinyl)-3,4-dihydro-2(1H)-, 6-(4-(3,4-Dimethoxybenzoyl)-1-piperazinyl)-3,4-dihydro-2(1H)-quinolone, 6-[4-(3,4-Dimethoxybenzoyl)-1-piperazinyl]-3,4-dihydro-2(1H)-quinolinone, 6-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]-3,4-dihydroquinolin-2(1H)-one, Arkin, Arkin-Z, Brn 5644229, Ccris 1451, Drg-0210, Opc-8212, Pieranometazine, Piperazine, 1-(3,4-dimethoxybenzoyl)-4-(1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)-, Piteranometozine, Unii-5Cow40Ev8M, Vesnarinona, Vesnarinona [Spanish], Vesnarinone [USAN:INN:JAN], Vesnarinonum, Vesnarinonum [Latin]
• CAS: 81840-15-5

Description

Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of cyclin-dependent kinase activity in p53-mediated cell cycle arrest.

• Brand: Targetmol

Chemical properties

• Molecular weight: 395.45
• Formula: C₂₂H₂₅N₃O₄
• Purity: 98.13%
• Color/Form: Solid