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N’-Nitrosonornicotine
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N’-Nitrosonornicotine

CAS: 80508-23-2

Ref. TM-T36709

5mg
262.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024

Product Information

Name:
N’-Nitrosonornicotine
Synonyms:
  • 1-Nitroso-2-(3-pyridyl)pyrrolidine
  • 3-(1-Nitroso-2-pyrrolidinyl)pyridine
  • Pyridine, 3-(1-nitroso-2-pyrrolidinyl)-
Description:

N’-Nitrosonornicotine is a tobacco-specific N-nitrosamine and carcinogen that has been found in unburned tobacco and cigarette smoke.1It induces the formation of DNA adducts in isolated rat nasal mucosa and esophagus. N’-Nitrosonornicotine induces tumor formation in rat esophagus and nasal cavity, mouse lung, forestomach, and trachea, and hamster trachea and forebrain. Urinary levels of N’-nitrosonornicotine are positively correlated with the risk of esophageal cancer in smokers.2
1.Hecht, S.S.Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosaminesChem. Res. Toxicol.11(6)559-603(1998) 2.Yuan, J.-M., Knezevich, A.D., Wang, R., et al.Urinary levels of the tobacco-specific carcinogen N’-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokersCarcinogenesis32(9)1366-1371(2011)

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
177.207
Formula:
C9H11N3O
Color/Form:
Solid
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Hazard Info

UN Number:
EQ:
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Forbidden to fly:
Hazard Info:
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LQ:

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