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4-oxo Docosahexaenoic Acid
CAS: 845673-74-7
Ref. TM-T36868
25µg | 121.00 € | ||
50µg | 218.00 € | ||
100µg | 407.00 € | ||
250µg | 898.00 € |
Product Information
4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 μM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 μM.
Chemical properties
Technical inquiry about: TM-T36868 4-oxo Docosahexaenoic Acid
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