8(E),10(E),12(Z)-Octadecatrienoic Acid

CAS: 5204-87-5

Ref. TM-T36887

Product Information

• Name: 8(E),10(E),12(Z)-Octadecatrienoic Acid
• Synonyms: (8E,10E,12Z)-8,10,12-Octadecatrienoic acid, (E,E,Z)-8,10,12-Octadecatrienoic Acid, 8,10,12-Octadecatrienoic acid, (8E,10E,12Z)-, 8,10,12-Octadecatrienoic acid, (Z,E,E)-, Calendic acid, Calendulic acid, a-Calendic Acid, trans,trans,cis-8,10,12-Octadecatrienoic acid

Description

8(E),10(E),12(Z)-Octadecatrienoic acid is a conjugated polyunsaturated fatty acid (PUFA) that has been found inC. officinalisseed oil and has anticancer activity.1,2,3It inhibits the growth of Caco-2 cells when used at concentrations ranging from 10 to 50 μM.28(E),10(E),12(Z)-Octadecatrienoic acid (10 μM) induces formation of thiobarbituric acid reactive substances (TBARS) and apoptosis in DLD-1 colorectal adenocarcinoma cells.3It also inhibits prostaglandin biosynthesis in sheep vesicular gland microsomes (IC50= 31 μM).4

• Brand: Targetmol

Chemical properties

• Molecular weight: 278.436
• Formula: C₁₈H₃₀O₂