13(S)-HpODE

CAS: 33964-75-9

Ref. TM-T37393

Product Information

• Name: 13(S)-HpODE
• Synonyms: (13S,9Z,11E)-13-Hydroperoxy-9,11-octadecadienoic acid, (9Z,11E,13S)-13-Hydroperoxy-9,11-octadecadienoic acid, (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoic acid, 13(S)-Hpode, 13(S)-Hydroperoxy-9Z,11E-octadecadienoic acid, 13(S)-Hydroperoxylinoleic acid, 13-<span class="text-smallcaps">L</span>-Hydroperoxy-9-cis,11-trans-octadecadienoic acid, 13-<span class="text-smallcaps">L</span>-Hydroperoxy-cis-9,trans-11-octadecadienoic acid, 13-<span class="text-smallcaps">L</span>-Hydroperoxylinoleic acid, 13-Hpod, 13-Hpode, 9,11-Octadecadienoic acid, 13-hydroperoxy-, (9Z,11E,13S)-, 9,11-Octadecadienoic acid, 13-hydroperoxy-, (E,Z)-<span class="text-smallcaps">L</span>-, 9,11-Octadecadienoic acid, 13-hydroperoxy-, [S-(E,Z)]-, Hpode, Linoleic acid 13(S)-hydroperoxide, Linoleic acid, 13-hydroperoxy-, <span class="text-smallcaps">L</span>-
• CAS: 33964-75-9

Description

13(S)-HpODE is produced by the oxidation of linoleic acid by lipoxygenase-1 (LO-1) in many plants including soybean, flaxseed, apples, and tea leaves,1,2 and by 15-LO in mammals.3 In plants, 13(S)-HpODE is the preferred substrate for the garlic bulb divinyl ether synthase.4 In mammalian tissues, 13(S)-HpODE is generally reduced to 13(S)-HODE,a compound which exhibits many biological activities.3 A direct action for 13(S)-HpODE has been demonstrated in Syrian hamster embryo cells where it stimulates EGF-dependent mitogenesis and up-regulation of EGF-dependent tyrosine phosphorylation.5 Membrane-esterified 13(S)-HpODE has been identified in human atherosclerotic plaques.6

• Brand: Targetmol

Chemical properties

• Molecular weight: 312.45
• Formula: C₁₈H₃₂O₄