Crocin II

CAS: 55750-84-0

Ref. TM-T3779

Product Information

• Name: Crocin II
• Synonyms: Crocin 2, Crocetin gentiobiosylglucosyl ester, Tricrocin, Crocin B, (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioate (non-preferred name), 1-[(2E,4E,6E,8E,10E,12E,14E)-B-D-Glucopyranosyl 2,6,11,15-Tetramethyl-2,4,6,8,10,12,14-Hexadecaheptaenedioate] 6-O-B-D-Glucopyranosyl-B-D-Glucopyranose, 8,8′-Diapo-ψ,ψ-carotenedioic acid, β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl 6-O-β-<smallcap>D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranosyl ester, Crocetin gentiobiosylglucosyl ester, Crocin 2, Crocin 3, Crocin B, Trans-Crocin 3, Trans-crocin-2, Tricrocin, all-trans-Crocetin β-<span class="text-smallcaps">D</smallcap>-gentiobiosyl-β-<smallcap>D</span>-glucosyl ester, trans-3-Gg-crocin, trans-Crocetin (β-<span class="text-smallcaps">D</smallcap>-gentiobiosyl) (β-<smallcap>D</span>-glucosyl) ester, trans-Crocetin (β-<span class="text-smallcaps">D</smallcap>-glucosyl)-(β-<smallcap>D</span>-gentiobiosyl) ester, β-<span class="text-smallcaps">D</smallcap>-Glucopyranose, 6-O-β-<smallcap>D</smallcap>-glucopyranosyl-, 1-[β-<smallcap>D</span>-glucopyranosyl (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate]
• CAS: 55750-84-0

Description

Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expression of iNOS and caspase-3. Crocin II can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite. Crocin II has antihyperlipidemic effect, may be due to the inhibition of pancreatic lipase and crocin, and its metabolite, Crocin II , can improve hyperlipidemia. Crocin has antidepressant effects by increasing CREB, BDNF and VGF levels in hippocampus.

• Brand: Targetmol

Chemical properties

• Molecular weight: 814.82
• Formula: C₃₈H₅₄O₁₉
• Purity: 99.19%
• Color/Form: Solid