YF-2 hydrochloride

CAS: 1312005-62-1

Ref. TM-T38711

Product Information

• Name: YF-2 hydrochloride
• Brand: Targetmol
• Description: YF-2 hydrochloride is a potent histone acetyltransferase activator that exhibits high selectivity and can pass through the blood-brain barrier. It specifically acetylates H3 in the hippocampus, with EC50 values of 2.75 μM, 29.04 μM, and 49.31 μM for CBP, PCAF, and GCN5, respectively. Notably, it does not affect HDAC activity. Moreover, YF-2 hydrochloride demonstrates promising anti-cancer and anti-Alzheimer's disease properties.

Chemical properties

• Molecular weight: 467.31
• Formula: C₂₀H₂₃Cl₂F₃N₂O₃
• Color/Form: Solid