
RORγt Inverse agonist 10
CAS:
Ref. TM-T40043

Product Information
Name:RORγt Inverse agonist 10
Brand:Targetmol
Description:RORγt Inverse agonist 10 is a highly potent, orally bioavailable compound that acts as an antagonist for the retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt). With an IC50 of 51 nM, it effectively inhibits RORγt activity, a key transcription factor regulating genes linked to psoriasis pathogenesis, including [IL-17A], [IL-22], and [IL-23R].
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Chemical properties
Molecular weight:572.512
Formula:C25H26F6N6O3
Color/Form:Solid