BIBB 515
CAS: 156635-05-1
Ref. TM-T4039
1mg | 55.00 € | ||
5mg | 118.00 € | ||
10mg | 183.00 € | ||
25mg | To inquire | ||
50mg | To inquire | ||
1ml*10 (DMSO) | 135.00 € |
Product Information
BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. OSC catalyzes the conversion of (3S)-2, 3-oxidosqualene to lanosterol, a precursor to cholesterol, in mammals and fungi. Total cholesterol was reduced by 19% in normolipemic hamsters at a dose of 55 mg/kg/day for 11 days and 25% in hyperlipemic hamsters at a dose of 148 mg/kg/day for 25 days.
Chemical properties
Technical inquiry about: TM-T4039 BIBB 515
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