Meclizine

CAS: 569-65-3

Ref. TM-T40652

Product Information

• Name: Meclizine
• Synonyms: Meclozine, (.+-.)-Meclizine, 1-(p-Chloro-α-phenylbenzyl)-4-(m-methylbenzyl) piperazine, 1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)diethylenediamine, 1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)piperazine, 1-(p-Chlorobenzohydryl)-4-(m-methylbenzyl) piperazine, 1-[(4-Chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine hydrate, 1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine, Ancolan, Bonine, Histametizyne, Meclozin, Meclozina, Navicalm, Neo-Istafene, Nsc 169189, Parachloramine, Piperazine, 1-(p-chloro-α-phenylbenzyl)-4-(m-methylbenzyl)-, Postafene, Ravelon, Sabari, Suprimal, U.C.B. 5062, Vomisseis
• CAS: 569-65-3

Description

Meclizine, also known as Meclozine, is a piperazine class H1 antagonist with antihistamine properties that inhibits the interaction of histamine at H1 receptors reversibly. It serves as an effective anti-motion sickness agent, able to cross the blood-brain barrier. Additionally, Meclizine acts as an agonist ligand for the mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR, making it useful in research on polyQ toxicity disorders, including Huntington's disease.

• Brand: Targetmol

Chemical properties

• Molecular weight: 390.95
• Formula: C₂₅H₂₇ClN₂
• Purity: 95.16%
• Color/Form: Solid