Calmodulin antagonist-1

CAS: 78957-84-3

Ref. TM-T40895

Product Information

• Name: Calmodulin antagonist-1
• Brand: Targetmol
• Description: Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist that effectively inhibits calmodulin-activated Ca 2+ -phosphodiesterase (PDE) with an IC 50 of 28 μM. This compound also competitively inhibits trypsin-treated Ca 2+ -PDE with respect to cyclic GMP, exhibiting an IC 50 of 375 μM and a K i value of 300 μM.

Chemical properties

• Molecular weight: 349.27
• Formula: C₁₄H₁₈Cl₂N₂O₂S
• Color/Form: Solid