CG 428
CAS: 2412055-93-5
Ref. TM-T41224
| 1mg | 172.00 € | ||
| 5mg | 415.00 € | ||
| 10mg | 609.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,281.00 € | ||
| 100mg | 1,753.00 € | ||
| 500mg | 3,511.00 € | ||
| 1ml*10 (DMSO) | 428.00 € |
Estimated delivery in United States, on Monday 17 Jun 2024
Product Information
Name:
CG 428
CAS:
Description:
CG 428 is a potent tropomyosin receptor Kinase (TRK) Degrader (uSMITETM) with a DC50 of 0.36 nM. CG 428 comprises an analog of the pan-TRK inhibitor GNF-8625 joined by a linker to the cereblon E3 ligase ligand pomalidomide. CG 428 shows selectivity for TRKA over TRKC and TRKB with Kds of 1nM, 4.2 nM, and 28 nM. CG 428 inhibits the growth of KM12 colon cancer cells with an IC50 of 2.9 nM.
Notice:
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Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
814.86
Formula:
C43H43FN10O6
Purity:
98.26%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TM-T41224 CG 428
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