CBL0137
CAS: 1197996-80-7
Ref. TM-T4126
| 1mg | 89.00 € | ||
| 5mg | 351.00 € | ||
| 10mg | 514.00 € | ||
| 25mg | 810.00 € | ||
| 50mg | 1,106.00 € | ||
| 100mg | 1,481.00 € | ||
| 1ml*10 (DMSO) | 351.00 € |
Estimated delivery in United States, on Friday 17 May 2024
Product Information
Name:
CBL0137
Synonyms:
- Curaxin 137, CBLC137
CAS:
Description:
CBL0137 (Curaxin 137), a metabolically stable curaxin, activates p53 (EC50: 0.37 μM) and inhibits NF-κB (EC50: 0.47 μM). It functionally inactivates the facilitates chromatin transcription complex (FACT), driving the effects on p53 and NF-κB and promoting cancer cell death. CBL0137 has broad anticancer activity in mice when administered orally, eradicates drug-resistant cancer stem cells, and potentiates the efficacy of gemcitabine in preClinicalal models of pancreatic cancer.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
336.43
Formula:
C21H24N2O2
Purity:
98%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
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