NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Theophylline
CAS:58-55-9
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial …
Formula:
C7H8N4O2
Purity:
99.47% - 99.97%
Color and Shape:
White Solid Powder
Molecular weight:
180.16
Ref: TM-T1083
| 500mg | 53.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
MRT67307
CAS:1190378-57-4
Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.
Formula:
C26H36N6O2
Purity:
99.25% - 99.79%
Color and Shape:
Solid
Molecular weight:
464.6
Ref: TM-T0097
| 1mg | 40.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 235.00 € | ||
| 50mg | 451.00 € | ||
| 100mg | 643.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Magnolol
CAS:528-43-8
Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks …
Formula:
C18H18O2
Purity:
100%
Color and Shape:
A Bioactive Compound Found In The Bark Of The Houpu Magnolia
Molecular weight:
266.33
Ref: TM-T3000
| 10mg | 51.00 € | ||
| 25mg | 76.00 € | ||
| 50mg | 99.00 € | ||
| 100mg | 154.00 € | ||
| 500mg | 362.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
BAY-985
CAS:2409479-29-2
BAY-985: potent oral TBK1/IKKε inhibitor; IC50s: TBK1 (2/30 nM), IKKε (2 nM); has antitumor properties.
Formula:
C27H30F3N9O
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
553.58
Ref: TM-T10477
| 1mg | 169.00 € | ||
| 5mg | 346.00 € | ||
| 10mg | 554.00 € | ||
| 25mg | 889.00 € | ||
| 50mg | 1,198.00 € | ||
| 100mg | 1,613.00 € | ||
| 1mL*10mM (DMSO) | 428.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Guaiacol
CAS:90-05-1
Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown …
Formula:
C7H8O2
Purity:
99.83%
Color and Shape:
Colourless To Pale Yellow Solid Crystalline
Molecular weight:
124.14
Ref: TM-T1301
| 500mg | 54.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Shikonin
CAS:517-89-5
Shikonin: TMEM16A inhibitor (IC50: 6.5μM), targets PKM2, suppresses NF-κB, inhibits TNF-α, and reduces exosome secretion.
Formula:
C16H16O5
Purity:
98.14% - 99.9%
Color and Shape:
Solid
Molecular weight:
288.3
Ref: TM-T1125
| 5mg | 35.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 141.00 € | ||
| 100mg | 210.00 € | ||
| 200mg | 319.00 € | ||
| 500mg | 533.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
α-Lipoic Acid
CAS:1077-28-7
α-Lipoic Acid, a sulfur-containing octanoic acid derivative, is biosynthesized from linoleic acid and used in …
Formula:
C8H14O2S2
Purity:
98.39%
Color and Shape:
Forms Yellowish Flakes Light Yellow To Yellow Powder
Molecular weight:
206.33
Ref: TM-T0200
| 1g | 34.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Urolithin B
CAS:1139-83-9
Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in …
Formula:
C13H8O3
Purity:
99.45%
Color and Shape:
Solid
Molecular weight:
212.2
Ref: TM-T13265
| 25mg | 49.00 € | ||
| 50mg | 78.00 € | ||
| 100mg | 113.00 € | ||
| 500mg | 271.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Mevastatin
CAS:73573-88-3
Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium …
Formula:
C23H34O5
Purity:
97.96%
Color and Shape:
White-Yellowish To Yellow Powder Solid Powder
Molecular weight:
390.51
Ref: TM-T0683
| 50mg | 55.00 € | ||
| 100mg | 83.00 € | ||
| 500mg | 207.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Baicalin
CAS:21967-41-9
Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, …
Formula:
C21H18O11
Purity:
90.08% - 98.96%
Color and Shape:
Yellow Powder
Molecular weight:
446.36
Ref: TM-T2775
| 50mg | 41.00 € | ||
| 100mg | 50.00 € | ||
| 500mg | 64.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
SN50 acetate (213546-53-3 free base)
SN50 acetate is a cell permeable inhibitor of NF-κB translocation.
Formula:
C131H234N36O31S
Purity:
99.86%
Color and Shape:
Solid
Molecular weight:
2841.55
Ref: TM-T12942L
| 1mg | 51.00 € | ||
| 5mg | 179.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 430.00 € | ||
| 50mg | 612.00 € | ||
| 100mg | 813.00 € | ||
| 200mg | 1,074.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Dihydroartemisinin
CAS:71939-50-9
Dihydroartemisinin (Artenimol) is a metabolite of artemisinin.
Formula:
C15H24O5
Purity:
99.41% - 99.72%
Color and Shape:
White Solid
Molecular weight:
284.35
Ref: TM-T0607
| 20mg | 39.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
IMD-0560
CAS:439144-66-8
IMD-0560 is a novel inhibitor of IκB kinase β.
Formula:
C15H8BrF6NO2
Purity:
99.51%
Color and Shape:
Solid
Molecular weight:
428.12
Ref: TM-T15564
| 1mg | 43.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 236.00 € | ||
| 50mg | 354.00 € | ||
| 100mg | 485.00 € | ||
| 200mg | 667.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Articaine hydrochloride
CAS:23964-57-0
Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.
Formula:
C13H21ClN2O3S
Purity:
99.88%
Color and Shape:
White Crystalline Powder
Molecular weight:
320.84
Ref: TM-T2131
| 1g | 276.00 € | ||
| 25mg | 36.00 € | ||
| 50mg | 52.00 € | ||
| 100mg | 83.00 € | ||
| 200mg | 113.00 € | ||
| 500mg | 184.00 € | ||
| 1mL*10mM (DMSO) | 46.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Erdosteine
CAS:84611-23-4
Erdosteine (RV 144), a mucolytic thiol, modulates mucus and aids expectoration, reduces cough, and protects …
Formula:
C8H11NO4S2
Purity:
99.43% - 99.63%
Color and Shape:
White Or Almost White Crystalline Powder
Molecular weight:
249.31
Ref: TM-T1229
| 1g | 95.00 € | ||
| 100mg | 36.00 € | ||
| 500mg | 72.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Methylthiouracil
CAS:56-04-2
Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and …
Formula:
C5H6N2OS
Purity:
100% - 99.89%
Color and Shape:
Crystals Saturated Aqueous Solution Is Neutral Or Slightly Acidic (Ntp 1992)
Molecular weight:
142.18
Ref: TM-T0304
| 25mg | 52.00 € | ||
| 50mg | 59.00 € | ||
| 100mg | 85.00 € | ||
| 200mg | 130.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
DMAPT
CAS:870677-05-7
DMAPT is a water-soluble PTL analogue, orally active NF-κB inhibitor with 1.7 μM LD50 in …
Formula:
C17H27NO3
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
293.4
Ref: TM-T11060
| 5mg | 51.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Tyloxapol
CAS:25301-02-4
Tyloxapol (Triton WR1339) is a non-ionic liquid polymer used as a surfactant.
Formula:
C70H124O13
Purity:
polymer - polymer
Color and Shape:
Clear Light Yellow Viscous Liquid
Molecular weight:
137.18
Ref: TM-T0307
| 1g | 57.00 € | ||
| 200mg | 35.00 € | ||
| 500mg | 49.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Mangiferin
CAS:4773-96-0
Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.
Formula:
C19H18O11
Purity:
96.74% - 98.30%
Color and Shape:
Light Yellow Powder
Molecular weight:
422.34
Ref: TM-T3012
| 10mg | 45.00 € | ||
| 25mg | 77.00 € | ||
| 50mg | 95.00 € | ||
| 100mg | 125.00 € | ||
| 500mg | 304.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Sulindac
CAS:38194-50-2
Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.
Formula:
C20H17FO3S
Purity:
99.32% - 99.49%
Color and Shape:
Yellow Solid
Molecular weight:
356.41
Ref: TM-T0459
| 50mg | 52.00 € | ||
| 100mg | 56.00 € | ||
| 200mg | 76.00 € | ||
| 500mg | 94.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
