L-Histidine monohydrochloride monohydrat

CAS: 5934-29-2

Ref. TM-T4826

Product Information

• Name: L-Histidine monohydrochloride monohydrat
• Synonyms: LHistidine monohydrochloride monohydrat, <span class="text-smallcaps">L</span>-Histidine hydrochloride monohydrate, <span class="text-smallcaps">L</span>-Histidine monohydrate monohydrochloride, <span class="text-smallcaps">L</span>-Histidine, hydrochloride, hydrate (1:1:1), <span class="text-smallcaps">L</span>-Histidine, monohydrochloride, monohydrate, H-His-OH*HCl*H2O, Histidine, monohydrochloride, monohydrate, <span class="text-smallcaps">L</span>-, L-Histidine Hydrochloride Monohydrate, L-Histidine hcl Monohydrate, L-histidine hydrochloride hydrate

Description

Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids, i.e., the building blocks of proteins. It is classified as a charged, polar because of the hydrophilic nature of the imidazole side chain. L-Histidine is a positively charged (pKa 6.5) aromatic amino acid. Histidine residues are often found in enzyme active sites, where the chemistry of the imidazole ring of histidine makes it a nucleophile and a good acid/base catalyzer. Histidine is special in that its biosynthesis is inherently linked to the pathways of nucleotide formation. In the first step of histidine synthesis, PRPP (5-phosphoribosyl-alpha-pyrophosphate) condenses with ATP to form a purine, N1-5'-phosphoribosyl ATP, in a reaction that is driven by the subsequent hydrolysis of the pyrophosphate that condenses out. Glutamine plays a role as an amino group donor resulting in the formation of 5-aminoamidazole-4-carboximide ribonucleotide (ACAIR), which is an intermediate in purine biosynthesis. Hisitidne is catabolized by the enzyme histidine ammonia-lyase which converts histidine into ammonia and urocanic acid.

• Brand: Targetmol

Chemical properties

• Molecular weight: 209.63
• Formula: C₆H₁₂ClN₃O₃
• Purity: 99.31%
• Color/Form: White Crystals