Resibufogenin

CAS: 465-39-4

Ref. TM-T4A2458

Product Information

• Name: Resibufogenin
• Synonyms: Bufogenin, Recibufogenin, (3Beta,5Beta,15Beta)-3-Hydroxy-14,15-Epoxybufa-20,22-Dienolide, (3Beta,5Beta,8Xi,9Xi,15Beta)-3-Hydroxy-14,15-Epoxybufa-20,22-Dienolide, (3β,5β,15β)-14,15-Epoxy-3-hydroxybufa-20,22-dienolide, 14,15β-Epoxy-3β-hydroxy-5β-bufa-20,22-dienolide, 3-Hydroxy-14,15-Epoxybufa-20,22-Dienolide, 3β-Hydroxy-14,15β-epoxy-5β-bufa-20,22-dienolide, 5β-Bufa-20,22-dienolide, 14,15β-epoxy-3β-hydroxy-, Bufa-20,22-dienolide, 14,15-epoxy-3-hydroxy-, (3β,5β,15β)-, NSC 90783, Recibufogenin, Resinobufagin, Respigon
• CAS: 465-39-4

Description

1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system. 3. Resibufogenin corrects hypertension in a rat model of human preeclampsia, it not only prevents the advent of hypertension and proteinuria, but also the development of intrauterine growth restriction.4. Resibufogenina's major metabolic pathway in the human liver is CYP3A4 dominantly mediated 5β-hydroxylation .

• Brand: Targetmol

Chemical properties

• Molecular weight: 384.51
• Formula: C₂₄H₃₂O₄
• Purity: 98.78%
• Color/Form: White To Off-White Solid