N-Acetyl-L-glutamic acid

CAS: 1188-37-0

Ref. TM-T5267

Product Information

• Name: N-Acetyl-L-glutamic acid
• Synonyms: Ac-L-Glu-OH, N-Acetylglutamic acid, (2S)-2-(acetylamino)pentanedioate, (2S)-2-Acetamidopentanedioic acid, <span class="text-smallcaps">L</span>-Glutamic acid, N-acetyl-, <span class="text-smallcaps">L</span>-N-Acetylglutamic acid, Ac-Glu-OH, Ac-Gly, Acetyl-L-glutamic acid, Acetylglutamic acid, Glutamic acid, N-acetyl-, <span class="text-smallcaps">L</span>-, N-Acetyl-<span class="text-smallcaps">L</span>-glutamic acid, N-Acetyl-<span class="text-smallcaps">L</span>-glutaminic acid, N-Acetyl-L-glutamate, N-Acetyl-S-glutamic acid, N-Acetylglutamate, N-acetylglutamic acid, α-(N-Acetyl)-<span class="text-smallcaps">L</span>-glutamic acid
• CAS: 1188-37-0

Description

N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phosphate synthetase in the urea cycle. A deficiency in N-acetyl glutamate synthase or a genetic mutation in the gene coding for the enzyme will lead to urea cycle failure in which ammonia is not converted to urea, but rather accumulated in the blood leading to the condition called Type I hyperammonemia.

• Brand: Targetmol

Chemical properties

• Molecular weight: 189.17
• Formula: C₇H₁₁NO₅
• Purity: 99.67%
• Color/Form: Solid