Semagacestat
CAS: 425386-60-3
Ref. TM-T6125
| 2mg | 40.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 344.00 € | ||
| 100mg | 510.00 € | ||
| 1ml*10 (DMSO) | 52.00 € |
Estimated delivery in United States, on Thursday 16 May 2024
Product Information
Name:
Semagacestat
Synonyms:
- LY450139
- (2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide
- (2S)-2-hydroxy-3-methyl-N-[(1S)-1-methyl-2-{[(1S)-3-methyl-2-oxo-2,3,4,5-tetrahydro-1H-3-benzazepin-1-yl]amino}-2-oxoethyl]butanamide
- Butanamide, 2-hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]-, (2S)-
- Ly 450139
CAS:
Description:
Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
361.44
Formula:
C19H27N3O4
Purity:
99.11%
Color/Form:
Solid
InChI:
InChI=1S/C19H27N3O4/c1-11(2)16(23)18(25)20-12(3)17(24)21-15-14-8-6-5-7-13(14)9-10-22(4)19(15)26/h5-8,11-12,15-16,23H,9-10H2,1-4H3,(H,20,25)(H,21,24)/t12-,15-,16-/m0/s1
InChI key:
InChIKey=PKXWXXPNHIWQHW-RCBQFDQVSA-N
SMILES:
CC(C)[C@H](O)C(=O)N[C@@H](C)C(=O)N[C@@H]1C(=O)N(C)CCc2ccccc21
MDL:
Melting point:
Boiling point:
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Density:
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EINECS:
Merck:
HS code:
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