Estimated delivery in United States, on Thursday 30 May 2024
Product Information
Name:
Indoximod
Synonyms:
- NLG-8189, Indoximod (NLG-8189）, 1-Methyl-D-tryptophan
- 1-Methyl-D-Trp
CAS:
Description:
Indoximod (Indoximod (NLG-8189)) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
218.25
Formula:
C12H14N2O2
Purity:
99.5%
Color/Form:
Solid
InChI:
InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m1/s1
InChI key:
InChIKey=ZADWXFSZEAPBJS-SNVBAGLBSA-N
SMILES:
Cn1cc(C[C@@H](N)C(=O)O)c2ccccc21
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TM-T6543 Indoximod
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