Rotundine

CAS: 483-14-7

Ref. TM-T6648

Product Information

• Name: Rotundine
• Synonyms: Gindarine, L-Tetrahydropalmatine, Caseanine, (-)-Tetrahydropalmatine, (-)-2,3,9,10-Tetramethoxyberbine, (-)-Corydalis B, (-)-Rotundine, (-)-S-Tetrahydropalmatine, (-)-Tetrahydropalmatine, (13AS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline, (13aS)-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine, 13aa-Berbine, 2,3,9,10-tetramethoxy-(8CI), 13aα-Berbine, 2,3,9,10-tetramethoxy-, 6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-,(S)-, Caseanine, Cyclanoline, O,O-dimethyl-N-demethyl-, Cyclanoline, O,O-dimethyl-N-demethyl- (6CI), Gindarine, Gindarine (7CI), Hyndarine, N-Demethyl-O,O'-dimethylcyclanoline, N-Demethyl-O,O'-dimethylsteponine, Palmatine, tetrahydro-, (-)-, Rotundine (Stephania), (-)-, l-Tetrahydropalmatine
• CAS: 483-14-7

Description

Rotundine (Gindarine) (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.

• Brand: Targetmol

Chemical properties

• Molecular weight: 355.43
• Formula: C₂₁H₂₅NO₄
• Purity: 100%
• Color/Form: Off-White Solid
• InChI: InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3/t17-/m0/s1
• InChI key: InChIKey=AEQDJSLRWYMAQI-KRWDZBQOSA-N
• SMILES: COc1cc2c(cc1OC)[C@@H]1Cc3ccc(OC)c(OC)c3CN1CC2