WYE-354
CAS: 1062169-56-5
Ref. TM-T6731
5mg | 50.00 € | ||
10mg | 83.00 € | ||
25mg | 152.00 € | ||
50mg | 275.00 € | ||
100mg | 356.00 € | ||
1ml*10 (DMSO) | 51.00 € |
Product Information
- WYE 354, WYE354
- 4-[6-[4-[(Methoxycarbonyl)amino]phenyl]-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinecarboxylic acid methyl ester
- Methyl 4-[6-{4-[(methoxycarbonyl)amino]phenyl}-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinecarboxylate
WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
Chemical properties
Technical inquiry about: TM-T6731 WYE-354
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.