Product Information
- 5-(2-Hydroxyethyl)-3-[(4-hydroxy-2-methyl-5-pyrimidinyl)methyl]-4-methylthiazolium chloride, hydrochloride
- 5-(2-Hydroxyethyl)-3-[(4-hydroxy-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium chloride hydrochloride (1:1:1)
- Hydroxythiamine chloride hydrochloride
- Oxythiamine chloride hydrochloride
- Thiazolium, 3-[(1,4-dihydro-2-methyl-4-oxo-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride, monohydrochloride
- Thiazolium, 3-[(1,6-dihydro-2-methyl-6-oxo-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride, hydrochloride (1:1:1)
- Thiazolium, 5-(2-Hydroxyethyl)-3-[(4-Hydroxy-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-, Chloride, Hydrochloride (1:1:1)
- Thiazolium, 5-(2-hydroxyethyl)-3-(4-hydroxy-2-methyl-5-pyrimidylmethyl)-4-methyl-, chloride, -HCl
- Thiazolium, 5-(2-hydroxyethyl)-3-[(4-hydroxy-2-methyl-5-pyrimidinyl)methyl]-4-methyl-, chloride, hydrochloride
- Thiazolium, 5-(2-hydroxyethyl)-3-[(4-hydroxy-2-methyl-5-pyrimidinyl)methyl]-4-methyl-, chloride, monohydrochloride
- See more synonyms
Oxythiamine chloride HCl is a thiamine antimetabolite that has anticancer activities. It is converted by thiamine pyrophosphokinase to oxythiamine pyrophosphate, a transketolase inhibitor. Oxythiamine decreases transketolase activity in breast cancer. It inhibits the nonoxidative synthesis of ribose and decreases RNA and DNA synthesis in pancreatic cancer. In vivo, oxythiamine induces cell cycle arrest at the G1 phase and apoptosis in an adenocarcinoma model. Oxythiamine, in combination with sorafenib, reduces tumor growth in an SMMC mouse xenograft model and has also been used to induce thiamine deficiency in mice.
Chemical properties
Technical inquiry about: TM-T71783 Oxythiamine chloride HCl
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
