Estimated delivery in United States, on Monday 15 Jul 2024
Product Information
Name:
HDAC-IN-53
CAS:
Description:
HDAC-IN-53 is an orally active, selective inhibitor of HDAC1-3, demonstrating IC50 values of 47 nM, 125 nM, and 450 nM, respectively. It exhibits no inhibitory effects on class II HDACs (HDAC4, 5, 6, 7, 9; IC50 >10 μM). The compound induces caspase-dependent apoptosis and significantly hampers the growth of human tumor xenografts in nude mice, as well as murine tumor growth in immune-competent mice with MC38 colon cancer [1].
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
461.9
Formula:
C23H20ClN7O2
Purity:
98%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TM-T74783 HDAC-IN-53
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