Estimated delivery in United States, on Monday 26 Aug 2024
Product Information
Name:
TWIK-1/TREK-1-IN-1
CAS:
Description:
Compound 2a, identified as TWIK-1/TREK-1-IN-1, acts as an inhibitor of the TREK-1, a two-pore domain potassium channel (K2p) that forms TREK-1 homodimers and TWIK-1/TREK-1 heterodimers, both significant for its role as an antidepressant target. Furthermore, TWIK-1/TREK-1-IN-3, a related compound, selectively inhibits these channels with IC50 values of 9.36 μM for TREK-1 homodimers and 14.6 μM for TWIK-1/TREK-1 heterodimers, demonstrating antidepressant-like effects [1].
Notice:
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Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
395.42
Formula:
C21H24F3NO3
Purity:
98%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TM-T78868 TWIK-1/TREK-1-IN-1
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