Estimated delivery in United States, on Thursday 29 Aug 2024
Product Information
Name:
mHTT-IN-2
Description:
mHTT-IN-2 (compound 27) is a potent inhibitor of mutant huntingtin protein (mHTT), with an EC50 value of 0.066 μM. It specifically modulates the splicing of HTT RNA exons [49-50], acting as a splicing regulator for the HTT gene. Demonstrating inhibitory effects both in vitro and in vivo, mHTT-IN-2 has been tested in human HD stem cells and mouse BACHD models. Additionally, it is applicable in the investigation of branaplam-related peripheral neuropathy [1].
Notice:
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Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
395.43
Formula:
C20H22FN7O
Purity:
98%
MDL:
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HS code:
Technical inquiry about: TM-T79717 mHTT-IN-2
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