Product Information
Name:LY303511 hydrochloride
Brand:Targetmol
Description:LY303511, a structural analog of LY294002, selectively inhibits mTOR-dependent phosphorylation of S6K, unlike its counterpart, which acts as a phosphatidylinositol 3-kinase (PI3K) inhibitor. It effectively reduces cell proliferation in human lung epithelial adenocarcinoma cells by hindering G2/M phase progression and suppressing casein kinase 2 activity. Additionally, LY303511 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sensitivity in HeLa cells resistant to TRAIL-induced apoptosis and blocks voltage-gated potassium (Kv) channels.
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Chemical properties
Molecular weight:379.28
Formula:C19H20Cl2N2O2
Color/Form:Solid
Technical inquiry about: LY303511 hydrochloride
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