Product Information
Name:HA-14-1
Brand:Targetmol
Description:HA-14-1, a small molecule, binds the surface pocket of Bcl-2 proteins (IC50= ~ 9 µM), including Bcl-xl and Bcl-W, and disrupts their interaction with the Bak peptide. This action induces apoptosis by activating Apaf-1 and caspase-9 and -3. Additionally, HA-14-1 effectively induces apoptosis in human acute myeloid leukemia (HL-60) cells, with a 50 µM concentration resulting in a 90% loss of cell viability.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:409.2
Formula:C17H17BrN2O5
Color/Form:Solid
Technical inquiry about: HA-14-1
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