Product Information
Name:(E)-2-Hexadecenal
Synonyms:
- trans-2-Hexadecenal
Brand:Targetmol
Description:Sphingosine-1-phosphate (S1P), a bioactive lipid crucial in numerous signaling pathways, undergoes irreversible degradation by membrane-bound S1P lyase, producing (E)-2-Hexadecenal, a derivative of sphingolipid breakdown. This compound can be oxidized to (2E)-hexadecenoic acid by long-chain fatty aldehyde dehydrogenase before being activated through linkage to coenzyme A. Notably, (E)-2-Hexadecenal induces cytoskeletal reorganization, leading to cell rounding, detachment, activation of JNK pathway targets, and ultimate apoptosis in a variety of cell types. Furthermore, it readily forms aldehyde-derived DNA adducts through reactions with deoxyguanosine and DNA.
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Chemical properties
Molecular weight:238.415
Formula:C16H30O
Color/Form:Solid
Technical inquiry about: (E)-2-Hexadecenal
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