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Doripenem hydrate

CAS:

Ref. TM-T84433

Doripenem hydrate
Targetmol

Product Information

Name:Doripenem hydrate
Synonyms:
  • S 4661
Brand:Targetmol
Description:Doripenem is a broad-spectrum carbapenem antibiotic effective against both Gram-negative and Gram-positive bacteria, such as S. aureus, S. pneumoniae, E. coli, and K. pneumoniae, with minimum inhibitory concentrations (MICs) ranging from less than 0.015 to 0.3 µg/ml. It has been proven to reduce the viable bacteria count in mouse lung models of chronic P. aeruginosa respiratory tract infection at a dosage of 100 mg/kg per day. Doripenem operates by inhibiting bacterial cell wall synthesis through the formation of stable acyl-enzyme complexes with penicillin-binding proteins, leading to their inactivation. This compound has been utilized in various formulations for the treatment of bacterial infections.
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Chemical properties

Molecular weight:420.51
Formula:C15H24N4O6S2XH2O
Color/Form:Solid

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