Product Information
Name:NBD-FTY720 phenoxy hydrochloride
Brand:Targetmol
Description:FTY720, an immune modulator, down-regulates sphingosine-1-phosphate (S1P) receptors, enhances the activity of sphingosine transporter Abcb1 and leukotriene C4 transporter Abcc1, and inhibits cytosolic phospholipase A2 activity. Its efficacy relies on in vivo phosphorylation by sphingosine kinases, resulting in FTY720-phosphate which also down-regulates S1P receptors. NBD-FTY720, a fluorescently-labeled analog of FTY720, retains the hydroxy methyl side chain targeted for phosphorylation, suggesting potential phosphorylation in vivo.
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Chemical properties
Molecular weight:510
Formula:C23H31N5O6HCl
Color/Form:Solid
Technical inquiry about: NBD-FTY720 phenoxy hydrochloride
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