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(±)11(12)-EpETE

CAS:

Ref. TM-T84501

(±)11(12)-EpETE
Targetmol

Product Information

Name:(±)11(12)-EpETE
Synonyms:
  • (±)11,12-EEQ
Brand:Targetmol
Description:Eicosapentaenoic acid (EPA) is metabolized into epoxyeicosatetraenoic acids (EpETE) by multiple cytochrome P450 isoforms. The predominant compound of this epoxygenase pathway, (±)17(18)-EpETE, induces relaxation in vascular and airway smooth muscles through its action on large conductance Ca2+-activated K+ (BKCa) channels, specifically by binding to the BKα channel subunits. Another notable epoxygenase pathway derivative, (±)11(12)-EpETE, also generated from EPA via CYP450 activity in both in vitro and in vivo studies, has biological and physiological roles that are yet to be fully elucidated.
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Chemical properties

Molecular weight:318.5
Formula:C20H30O3
Color/Form:Solid

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