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5(S)-HEPE

CAS:

Ref. TM-T84567

5(S)-HEPE
Targetmol

Product Information

Name:5(S)-HEPE
Brand:Targetmol
Description:5(S)-HEPE, an active metabolite of eicosapentaenoic acid (EPA), is produced via the action of 5-lipoxygenase (5-LO). This compound functions as an agonist for G protein-coupled receptor 119 (GPR119), promoting cAMP accumulation in CHO-K1 cells expressing human GPR119 at 10 µM concentration. Additionally, 5(S)-HEPE enhances glucose-stimulated insulin secretion from MING6 insulinoma pancreatic islets and glucagon-like peptide 1 (GLP-1) secretion from HuTu 80 adenocarcinoma cells at the same concentration. Notably, serum levels of 5(S)-HEPE are increased in hyperlipidemia patients.
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Chemical properties

Molecular weight:318.5
Formula:C20H30O3
Color/Form:Solid

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