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Rp-dGTPαS

CAS:

Ref. TM-T84664

Rp-dGTPαS
Targetmol

Product Information

Name:Rp-dGTPαS
Synonyms:
  • Rp-dGTP-α-S
Brand:Targetmol
Description:Rp-dGTPαS, an enantiomer of the dNTPαS nucleotide, serves as the substrate for SAMHD1, a critical regulator of cellular dNTP levels that curtails the replication of viruses (HIV-1, etc.) in CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex facilitates the hydrolysis of Rp-dGQTPαS into 2'-deoxynucleosides and triphosphates [1].
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Chemical properties

Molecular weight:523.25
Formula:C10H16N5O12P3S
Color/Form:Solid

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