Product Information
Name:(S)-Ro 32-0432
Synonyms:
- Ro 32-0432 hydrochloride
Brand:Targetmol
Description:(S)-Ro 32-0432 is a potent, selective inhibitor of protein kinase C (PKC) and G protein-coupled receptor kinase 5 (GRK5), demonstrating ATP-competitive and oral activity. It presents IC50 values of 9.3 nM for PKCα, 28 nM for PKCβI, 30 nM for PKCβII, 36.5 nM for PKCγ, and 108.3 nM for PKCε, showcasing its effectiveness against multiple PKC isoforms. Additionally, (S)-Ro 32-0432 inhibits T-cell activation, indicating its potential application in the research of chronic inflammatory and autoimmune diseases [1] [2].
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:489.01
Formula:C28H29ClN4O2
Color/Form:Solid
Technical inquiry about: (S)-Ro 32-0432
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