Product Information
- ara-CMP
- Ara-5'-CMP
- 1-beta-D-Arabinofuranosylcytosine 5'-monophosphate
- 1-beta-D-Arabinofuranosylcytosine 5'-phosphate
- 1beta-Arabino-furanosylcytosine-5'-monophosphoric acid, D-
- Arabinosylcytosine 5'-monophosphate
- Aracytidine 5'-monophosphate
- Aracytidine 5'-phosphate
- Cytarabine 5'-monophosphate
- Cytosine arabinoside 5'-monophosphate
- See more synonyms
- Cytosine arabinoside 5'-phosphate
- Cytosine arabinoside 5'MP
- Cytosine arabinoside monophosphate
- Nsc 99445
- 2(1H)-Pyrimidinone, 4-amino-1-(5-O-phosphono-beta-D-arabinofuranosyl)-
- Cytosine, 1-beta-D-arabinofuranosyl-, 5'-(dihydrogen phosphate) (8CI)
- 4-amino-1-(5-O-phosphono-beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
- 1-β-D-Arabinofuranosylcytosine 5'-monophosphate
Cytarabine 5′-monophosphate (ara-CMP), an active metabolite of the nucleoside analog cytarabine formed by deoxycytidine kinase, is incorporated into DNA by DNA polymerase α, significantly slowing DNA synthesis. It inhibits nuclear and mitochondrial DNA replication in S. cerevisiae at 15 mM and improves survival in an L1210 murine leukemia model at 3.5-75.1 mg/kg.
Chemical properties
Technical inquiry about: TM-T84932 Cytarabine 5′-monophosphate
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