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5α-Androstan-3β-ol
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5α-Androstan-3β-ol

CAS: 1224-92-6

Ref. TM-T84963

10mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Tuesday 11 Feb 2025

Product Information

Name:
5α-Androstan-3β-ol
Synonyms:
  • NSC 50887
  • (3Beta,5Alpha)-Androstan-3-Ol
  • (3β,5α)-Androstan-3-ol
  • 3beta-Hydroxy-5alpha-androstane
  • 3β-Hydroxy-5α-androstane
  • 5alpha-Androstan-3beta-ol
  • Androstan-3-ol
  • Androstan-3-ol, (3beta,5alpha)- (9CI)
  • Androstan-3-ol, (3β,5α)-
  • Nsc 50887
  • See more synonyms
Description:

5α-Androstan-3β-ol, a steroidal androgen, demonstrates selective interaction with cellular components, showing affinity for the androgen receptor (AR) with an IC50 of 1.7 µM and activating the pregnane X receptor (PXR) in HepG2 cells with an EC50 of 0.8 µM. It selectively inhibits the hydroxylase activities of 16α- and 6β-hydroxylase over 16β- or 7α-hydroxylase, with IC50 values of 70 and 110 µM, compared to >150 µM for the latter enzymes, indicating a specificity in its enzyme inhibition profile. Additionally, administration of this compound at a dosage of 30 mg/kg results in a decrease in testis weight and sperm production in mice, highlighting its biological effects on male reproductive parameters.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
276.46
Formula:
C19H32O
Color/Form:
Liquid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Technical inquiry about: TM-T84963 5α-Androstan-3β-ol

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