Product Information
- CGP 46700
- 1,2-Diethyl-3-hydroxypyridin-4-one
- 1,2-Diethyl-3-hydroxy-4(1H)-pyridinone
- CP94
- CGP 46700
- 4(1H)-Pyridinone, 1,2-diethyl-3-hydroxy-
- 1,2-diethyl-3-hydroxypyridin-4(1H)-one
CP94, an iron chelator, enhances protoporphyrin IX photobleaching and reduces the viability of A431 squamous epithelial carcinoma cells at a 150 µM concentration with photodynamic therapy (PDT) using protoporphyrin IX precursors such as aminolevulinic acid (ALA), methyl aminolevulinate (MAL), or hexylaminolevulinate (HAL). Additionally, CP94 (2 mg/ml in drinking water) lowers hepatic non-heme and ferritin-bound iron levels while increasing hepatic protoporphyrin levels in mice. It also counteracts ferrocene-induced rises in rat brain iron levels at a dosage of 100 mg/kg.
Chemical properties
Technical inquiry about: TM-T84999 CP94
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