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PON-PC

CAS:

Ref. TM-T85001

PON-PC
Targetmol

Product Information

Name:PON-PC
Synonyms:
  • 16:0/9:0-PC
Brand:Targetmol
Description:PON-PC, an oxidized phospholipid with a 9-carbon fatty acyl chain ending in an aldehyde at the sn-2 position, arises from the oxidation of palmitoyl oleoyl phosphatidylcholine (POPC) or through interaction with ozone in pulmonary surfactant. It is found in oxidized LDL. At a 40 µM concentration, PON-PC diminishes the production of TNF-α, nitric oxide (NO), and NADP+ in primary mouse alveolar macrophages and lowers the bactericidal capability of RAW 264.7 cells. Additionally, levels of PON-PC increase in the bronchoalveolar lavage fluid (BALF) of mice exposed to cigarette smoke or in older mice.
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Chemical properties

Molecular weight:649.4
Formula:C33H64NO9P
Color/Form:Solid

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