Product Information
- L-γ-Amino-β-hydroxybutyric Acid
- (3R)-4-Amino-3-hydroxybutanoic acid
- butanoic acid, 4-amino-3-hydroxy-, (3R)-
- (R)-4-Amino-3-Hydroxy-Butyric Acid
(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.
Chemical properties
Technical inquiry about: TM-T85014 (R)-4-Amino-3-hydroxybutyric Acid
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