Product Information
Name:Mca-SEVNLDAEFK(Dnp)
Brand:Targetmol
Description:Mca-SEVNLDAEFK(Dnp) is a peptide FRET substrate for Beta-secretase 1 (BACE-1), featuring the 'Swedish' Lys-Met/Asn-Leu mutation at the β-secretase cleavage site of the amyloid precursor protein (APP). Cleavage at the -Leu-Asp- site of Mca-SEVNLDAEFK(Dnp) releases the highly fluorescent 7-methoxycoumarin (Mca) fragment, which is freed from the quenching effect of the 2,4-dinitrophenyl (Dnp) internal quencher, leading to a significantly increased fluorescence intensity that is easily detectable.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1533.5
Formula:C68H88N14O27
Color/Form:Solid
Technical inquiry about: Mca-SEVNLDAEFK(Dnp)
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